SubtiBank SubtiBank
ydiO [2019-06-24 07:50:55]
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ydiO [2019-06-24 07:50:55]

similar to DNA-3-methyladenine glycosidase II
locus
BSU06060
pI
7.66
mw
48.75 kDa
protein length
427 aa Sequence Blast
gene length
1284 bp Sequence Blast
function
BsuM DNA modification
product
unknown
essential
yes
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.4|DNA restriction/ modification]
  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.5|Prophage 3]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • Gene

    Coordinates
    655,223 656,506

    Phenotypes of a mutant

  • essential [Pubmed|12682299], mutation is only possible in a ''[gene|4BD4CFB10700907DF1BBF3C9CFACAF573588E85F|ydiR]'', ''[gene|A8C606348C8C6FC3BB9786C06C9BFE9D3519A041|ydiS]'', or ''[gene|D36B91B3C8EAFEB80A7395C62A50A5F80B8CC5C5|ydjA]'' background (''i. e.'', in the absence of the BsuM DNA restriction system) [Pubmed|11751814]

    • The protein

    Protein family

  • [SW|Methyltransferase superfamily] (according to UniProt)

    • Structure

  • [PDB|3G7U] (from E. coli phage, 28% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|9EE25F97B2C6240E31BA1D5EEE9DA2D7940C9637|ydiO]-[gene|CEA337DD4C7DFC22247FDA7FA1E71356FB819C77|ydiP]
    description
    [Pubmed|11751814]

    regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [Pubmed|16267290], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]

    • regulation

  • induced by DNA damage ([protein|search|LexA]) [Pubmed|16267290]
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    References

  • 16267290,11751814,22092861